Hypodontia is commonly associated with which condition?

Hypodontia, defined as the developmental absence of one or more teeth, is frequently linked with various genetic and developmental conditions. One of the conditions most commonly associated with hypodontia is Down's syndrome, which is a genetic disorder caused by the presence of an extra chromosome 21. Individuals with Down's syndrome often present with various dental anomalies, including hypodontia.

This correlation arises due to the developmental delays and structural changes that affect dental formation in people with Down's syndrome. Their dental health shows a higher incidence of missing teeth, among other dental issues. The presence of hypodontia in these individuals can also be influenced by other factors, such as the overall growth development patterns typical for those with Down's syndrome.

In contrast, while conditions like Cleidocranial dysplasia and Papillon-Lefevre syndrome may also present with dental anomalies, they are not as widely recognized for hypodontia specifically. Cleidocranial dysplasia is more characterized by the retention of primary teeth and the absence of permanent teeth rather than hypodontia. Rickets, a condition caused by vitamin D deficiency, primarily affects bone health and leads to bone deformities rather than having a direct association with missing teeth like hypodontia.