Unilateral swelling in the floor of the mouth after meals is typically associated with which condition?

Unilateral swelling in the floor of the mouth after meals is typically associated with a sub-mandibular sialolith, which is a stone that forms in the salivary gland, specifically in the submandibular gland. When the salivary gland is stimulated, such as during or after meals, saliva is produced and attempts to flow through the duct. If there is a sialolith present, it can obstruct the flow of saliva, leading to swelling and discomfort in the area. This swelling tends to be more pronounced after eating due to the increased saliva production triggered by the act of eating.

In contrast, conditions like ranula, cysts, or mucocele may not have the same characteristic relationship to mealtime swelling. A ranula usually involves a bilateral presentation and may not be directly linked to meal stimulation. Cysts can present as localized swellings but are generally not associated with acute swelling linked to salivary flow. Mucoceles are typically related to minor salivary glands and can present in various locations; they are less likely to cause swelling after meals compared to the obstruction caused by a sialolith.