What is TRUE regarding Basal Cell Carcinoma?

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Basal Cell Carcinoma (BCC) primarily arises in the skin, particularly in areas that receive significant sun exposure, such as the face and neck. It is characterized by a local invasion rather than metastasis, meaning that while it can be aggressive and invade surrounding tissues, it rarely spreads to distant sites or organs.

The assertion regarding its occurrence in the oral mucosa can be considered accurate when adhering to the traditional definition of BCC, which primarily focuses on cutaneous manifestations. By this definition, BCC does not typically arise in the oral cavity or mucosal surfaces, making the statement true.

The other aspects are critical to understanding BCC's clinical behavior. Metastasis is not a common feature, and while BCC can cause local destruction, it typically does not erode bone unless it has progressed extensively. Furthermore, the incidence of BCC does not significantly vary between races in a way that would make it more common in specific ethnic groups like those categorized as 'oriental races.' Thus, the correct answer highlights an important limitation in the traditional understanding of where BCC occurs.

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