Which histological feature is typical of Lichen planus?

The histological feature that is typical of Lichen planus is the band of lymphocytes inflammation and hyperparakeratosis. In Lichen planus, a chronic inflammatory condition affecting the skin and mucous membranes, one can observe a band-like infiltrate of lymphocytes at the dermal-epidermal junction when examined under a microscope. This band of lymphocytes corresponds to the inflammatory response associated with the condition.

Additionally, hyperparakeratosis refers to the retention of nuclei in the stratum corneum, which is a common finding in Lichen planus. The combination of these features helps distinguish Lichen planus from other similar disorders.

Other options do not accurately portray the typical histological findings of Lichen planus. While smooth rete pegs and a thickened keratin layer may occur in other conditions, they do not specifically represent the characteristic features of Lichen planus. Similarly, immunofluorescence of a liquefied layer is not a standard finding in Lichen planus and is more associated with other conditions that involve different immunological mechanisms. Thus, the presence of a band of lymphocytes and hyperparakeratosis is what makes option B the correct choice for identifying typical histological features