Which of the following is NOT a result of a toxic dosage of local anesthetic?

Angioneurotic edema is not typically a result of a toxic dosage of local anesthetic. This condition is an allergic reaction that leads to swelling of the deeper layers of the skin, often affecting the face, lips, and throat. It is associated with histamine release in response to allergens or irritants rather than a direct consequence of local anesthetic overdose.

In contrast, hypotension, respiratory depression, and hypertension can all occur as a result of local anesthetic toxicity. Hypotension can occur due to vasodilation and depression of cardiac function, while respiratory depression can be linked to central nervous system effects if the anesthetic affects the brain and suppresses respiratory drive. Hypertension, although it might seem paradoxical, can also occur due to a compensatory mechanism or reflexive response to other physiological changes produced by local anesthetics, including increased sympathetic tone. Thus, angioneurotic edema stands out as a manifestation unrelated to the toxic effects of local anesthetics.